jeromelh
Junior
Posts: 202
Age: 81
Reg: 03-30-17
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Re: Canady 01-30-19 07:36 AM - Post#274128
In response to Mike Porter
With the massive number of deaths due to alcohol and opioids, it is important to remember that NO one has ever died of cannabis. In addition, if you take it as an oil or vape, you eliminate the toxins associated with smoking weed.
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1LotteryPick1969
Postdoc
Posts: 2262
Age: 73
Loc: Sandy, Utah
Reg: 11-21-04
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Re: Canady 01-30-19 07:59 AM - Post#274129
In response to jeromelh
With the massive number of deaths due to alcohol and opioids, it is important to remember that NO one has ever died of cannabis. In addition, if you take it as an oil or vape, you eliminate the toxins associated with smoking weed.
I agree that direct deterministic death from cannabis OD is unknown, but the stochastic relationship to death from myocardial infarction exists.
Journal of Cardiovascular Pharmacology and Therapeutics:
Acute coronary syndrome triggered by marijuana exposure may include angina pectoris, myocardial infarction, and sudden cardiac death.
Patients are being asked to get "clearance" from their cardiologist for medical marijuana, which of course is not possible.
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penn nation
Professor
Posts: 21086
Reg: 12-02-04
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Re: Canady 01-30-19 08:32 AM - Post#274130
In response to jeromelh
In addition, if you take it as an oil or vape, you eliminate the toxins associated with smoking weed.
Vaping is probably one of the most serious challenges facing our youth today. It is a gateway to a whole host of problems. Our schools are recognizing this and educating us (both students and parents) in ways that were so sorely lacking a generation ago.
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jeromelh
Junior
Posts: 202
Age: 81
Reg: 03-30-17
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01-30-19 12:37 PM - Post#274145
In response to penn nation
Hi Penn nation and Lottery
Thanks for your responses. However, both of you are not understanding cannabis and, in this case, medical cannabis (in my humble opinion).
First of all, the article cited is related to marijuana smoke (that is how I remember it). When you smoke a joint, you are exposed to many toxins such as carbon monoxide. Many of these toxins are known to cause cardiac spasm. When you use medical marijuana by sub-lingual or inhaler, you are not exposed to the toxins. The author is giving us the impression that it is related to cannabis but there is no basis for this conclusion. When you use a vape you use it once or twice a day only with one inhalation and this is not going to give rise to any problems such as encountered with those in vape stores.
Lottery you said “I agree that direct deterministic death from cannabis OD is unknown, but the stochastic relationship to death from myocardial infarction exists.â€
Opponents have been trying to prove for years that cannabis exposure can cause death and have utterly failed. And there is a reason for this. While there are more cannabis receptors in the brain than opioid receptors, there are NO cannabis receptors in the midbrain which I am sure you know controls respiratory and cardiac rate. There are numerous opioid receptors in the midbrain which explains death due to opioid overdose. With all of the people on medical marijuana in this country, we would have seen coronary spasm by now if it was causative.
Two years ago, I was an opponent of medical marijuana. Now I am an advocate.
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1LotteryPick1969
Postdoc
Posts: 2262
Age: 73
Loc: Sandy, Utah
Reg: 11-21-04
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01-30-19 01:09 PM - Post#274149
In response to jeromelh
Interesting.
I'm not interested in medical marijuana, just recreational, and only as an observer.
There are more ways to cause a heart attack than spasm.
From Cardiology and Therapeutics June 2018:
"Despite overwhelming public perception of the safety of these substances, an increasing number of serious cardiovascular adverse events have been reported in temporal relation to recreational cannabis use. These have included sudden cardiac death, vascular (coronary, cerebral and peripheral) events, arrhythmias and stress cardiomyopathy among others. Many of the victims of these events are relatively young men with few if any cardiovascular risk factors. However, there are reasons to believe that older individuals and those with risk factors for or established cardiovascular disease are at even higher danger of such events following exposure to cannabis. The pathophysiological basis of these events is not fully understood and likely encompasses a complex interaction between the active ingredients (particularly the major cannabinoid, Δ9-tetrahydrocannabinol), and the endo-cannabinoid system, autonomic nervous system, as well as other receptor and non-receptor mediated pathways. Other complicating factors include opposing physiologic effects of other cannabinoids (predominantly cannabidiol), presence of regulatory proteins that act as metabolizing enzymes, binding molecules, or ligands, as well as functional polymorphisms of target receptors. Tolerance to the effects of cannabis may also develop on repeated exposures at least in part due to receptor downregulation or desensitization."
The bold script added by me.
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Tiger69
Postdoc
Posts: 2801
Reg: 11-23-04
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01-30-19 01:15 PM - Post#274152
In response to jeromelh
This is an interesting discussion that deserves its own AMA thread.
Who believes that Princeton can survive a brief Cannady absence of, say, 5 games and then emerge stronger for the experience gained during his absence? Just wishful thinking?
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1LotteryPick1969
Postdoc
Posts: 2262
Age: 73
Loc: Sandy, Utah
Reg: 11-21-04
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01-30-19 01:19 PM - Post#274153
In response to Tiger69
This is an interesting discussion that deserves its own AMA thread.
Who believes that Princeton can survive a brief Cannady absence of, say, 5 games and then emerge stronger for the experience gained during his absence? Just wishful thinking?
Dunno. Just waiting to hear...........
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Tiger69
Postdoc
Posts: 2801
Reg: 11-23-04
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01-30-19 01:22 PM - Post#274154
In response to Tiger69
PS. In my modest past of perhaps a couple of dozen joint experiences I only experienced one occasion where I had a perceivable effect. And that was pleasant (sort of). Someone told a weak joke, but I laughed uncontrollably for nearly a half hour. Sadly, the usual effect was a sore throat.
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yoyo
Senior
Posts: 354
Reg: 03-25-09
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01-30-19 01:24 PM - Post#274155
In response to Tiger69
I like pot and I smoke it a lot
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HARVARDDADGRAD
Postdoc
Posts: 2685
Loc: New Jersey
Reg: 01-21-14
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01-30-19 02:06 PM - Post#274169
In response to yoyo
You might qualify for SCOTUS in the next administration then. Remember that mantra and keep repeating it in all future congressional hearings.
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palestra38
Professor
Posts: 32685
Reg: 11-21-04
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01-30-19 02:18 PM - Post#274174
In response to yoyo
Wasn't that line in the Lost Dr. Suess story? You know, the one about how the Onceler got to looking like an 80 year old Jerry Garcia?
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jeromelh
Junior
Posts: 202
Age: 81
Reg: 03-30-17
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01-30-19 02:37 PM - Post#274179
In response to palestra38
Sorry for the long post off subject . I will get off my soapbox
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1LotteryPick1969
Postdoc
Posts: 2262
Age: 73
Loc: Sandy, Utah
Reg: 11-21-04
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01-30-19 03:26 PM - Post#274185
In response to palestra38
Wasn't that line in the Lost Dr. Suess story?
Funny!
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penn nation
Professor
Posts: 21086
Reg: 12-02-04
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Canady 01-30-19 03:45 PM - Post#274186
In response to jeromelh
Jerome:
Don't get me wrong. I'm an advocate for medical marijuana and, for that matter, for marijuana's general legalization (assuming it is properly regulated).
It's just that the youth of our country get introduced relatively harmlessly to vaping via marijuana as you've described, which then makes them think it's no big deal in general (if said marijuana is legalized and properly regulated, even less of an issue since quality control is thereby not the primary concern). Then they move onto other stuff, and they are out of their league in no time.
OK, off my soapbox. We can take this up further in the OTB if desired.
Edited by penn nation on 01-30-19 03:46 PM. Reason for edit: No reason given.
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penn nation
Professor
Posts: 21086
Reg: 12-02-04
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01-30-19 03:48 PM - Post#274187
In response to HARVARDDADGRAD
You might qualify for SCOTUS in the next administration then. Remember that mantra and keep repeating it in all future congressional hearings.
Didn't work out so well for Douglas Ginsburg, though.
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Go Green
PhD Student
Posts: 1124
Age: 52
Reg: 04-22-10
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Re: Canady 01-31-19 02:11 PM - Post#274272
In response to jeromelh
it is important to remember that NO one has ever died of cannabis.
THat's not my recollection of what Nancy Reagan said on Diff'rent Strokes.
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palestra38
Professor
Posts: 32685
Reg: 11-21-04
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Re: Canady 01-31-19 02:12 PM - Post#274274
In response to Go Green
Or that landmark Dragnet in the late '60s (the second version with Harry Morgan and Jack Webb) where the stoned hippies forgot they had the baby in the bathtub.
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Go Green
PhD Student
Posts: 1124
Age: 52
Reg: 04-22-10
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Re: Canady 01-31-19 05:01 PM - Post#274300
In response to palestra38
Or that landmark Dragnet in the late '60s (the second version with Harry Morgan and Jack Webb) where the stoned hippies forgot they had the baby in the bathtub.
IMHO, Harry Morgan never got his due. It takes a actor of great talent to convincingly star on arguably the most conservative and most liberal (for their times, anyway) television shows.
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Eric Von Zipper
Senior
Posts: 343
Age: 71
Reg: 11-11-17
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Re: Canady 01-31-19 08:50 PM - Post#274318
In response to Go Green
Morgan, 81, was charged July 7 with misdemeanor spousal battery after a confrontation in their Brentwood home left Barbara Morgan, his 70-year-old wife of 10 years, bruised and bloodied.
Nice guy.
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bradley
PhD Student
Posts: 1842
Age: 74
Reg: 01-15-16
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02-01-19 09:59 AM - Post#274353
In response to Tiger69
This is an interesting discussion that deserves its own AMA thread.
Who believes that Princeton can survive a brief Cannady absence of, say, 5 games and then emerge stronger for the experience gained during his absence? Just wishful thinking?
I believe that the loss of Cannady for a minimum of the next 4 IL games will be very challenging and needless to say if he is gone for the season, it will be problematic if they participate in IvyMadness. Presently, there are not great options to replace Devin's 3 pt shooting, i.e. Wright, Schwieger etc. One partial hope is that DesRosiers and Much and possibly Johns starting shooting 3s' 7% higher than y-t-d.
For me and I realize that I am in the minority, IL regular season champion is what counts and if the Tigers get into IvyMadness in the 3rd or 4th slot and then win the silly tournament with Cannady, I simply do not care.
Cannady's absence will make it very very challenging to win the regular season but let's play the games to find out.
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